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Chem.2002,45, 5037 41
In the case of rAmy:AMY 3 R:G s , the histidine residues predicted as tautomer were: H226 (CTR), H41, H357 (G), 54, 183, 311 (G)
Without maintenance, the improvement typically diminishes gradually over 24 months as natural melanin production resumes
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